Aiming at the requirements of environmental monitoring, energy-saving and safety protection oflaboratory environment, an intelligent monitoring and control system is designed and developed, takingSTC12C5A60S2 single chip microcomputer as the core control unit.The number of people in the laboratory arecounted through the combination of infrared pyroelectric and ultrasonic sensor. Meanwhile , the temperaturehumidity and combustible gas concentration in the laboratory are monitored and displayed in real time. The system can be set to operate in working mode or protection mode.ln working mode , the light on and off andoutput the part of power are controlled according to whether the number of people in the laboratory is zero. Inthe protection mode if the number of people in the laboratory is not zero ,the system will send a message to theadministrator through the SlM module.In both modes ,the system can start sound and message alarm when thecombustible gas exceeds the standard. The system has the advantages of simple structure ,high performance andconvenient operation. lt can be used for the monitoring and protection of laboratories.