During the outbreak of the new coronary pneumonia, online teaching has become the best teaching method at present. In order to ensure the quality of online teaching, this article proposes a five-dimensional integrated teaching mode under the guidance of the "OBE" concept. The effective implementation of the "Five dimensions" (transform, experience, engage, evaluate, and improve) could ensure teaching quality of online classroom. This teaching mode provides the necessary theoretical support for the teachers' online teaching, and also has a positive effect on motivating students' enthusiasm for learning and achieving comprehensive training of students' capability.